| 抄録 |
Objective: Asymptomatic erosive esophagitis is a common, yet rarely reported disease. We investigated risk factors related to asymptomatic erosive esophagitis and the natural history of both endoscopic findings and reflux-related symptoms in subjects with asymptomatic erosive esophagitis. Method: On a retrospective basis, data was gathered from the subjects who had undergone endoscopic follow-up among subjects with erosive esophagitis at St. Vincent hospital. Results: The data of 313 subjects with erosive esophagitis were investigated. Most patients have mild esophagitis applicable to grade A or B Los Angeles classification; 198 (63.3%) had reflux symptoms and 115 (36.7%) lacked typical and atypical symptoms. Using multiple logistic regression analysis, asymptomatic erosive esophagitis was associated with non-smoking (odds ratio (OR), 2.4; 95% CI, 1.4-3.9), and lower body mass index (OR, 1.5; 95% CI, 1.-2.4), while 26% of subjects had recurred reflux related symptoms. Subjects at younger age had a greater tendency to have reflux related symptoms. Conclusion: Being a nonsmoker and having a lower BMI are associated with asymptomatic reflux esophagitis. Most asymptomatic subjects had regression or unchanged in endoscopy finding. Young age with asymptomatic erosive esophagitis might be treated properly. |
