セッション情報 The 2nd JSGE International Topic Conference Poster Session

Upper GI:Clinical Approach

タイトル IT-P-01:

Pathological Investigation of Endoscopically Suspected Esophageal Metaplasia

演者 Hashimoto Takashi(Department of Gastroenterology, Juntendo University School of Medicine, Japan)
共同演者 Asaoka Daisuke(Department of Gastroenterology, Juntendo University School of Medicine, Japan), Morimoto Takashi(Departments of Human Pathology, Juntendo University School of Medicine, Japan), Murakami Takashi(Departments of Human Pathology, Juntendo University School of Medicine, Japan), Lee Se-yong(Departments of Human Pathology, Juntendo University School of Medicine, Japan), Hidaka Yasuhiro(Department of Gastroenterology, Juntendo University School of Medicine, Japan), Nagahara Akihito(Department of Gastroenterology, Juntendo University School of Medicine, Japan), Yao Takashi(Departments of Human Pathology, Juntendo University School of Medicine, Japan), Watanabe Sumio(Department of Gastroenterology, Juntendo University School of Medicine, Japan)
抄録 Aim:Barrett’s mucosa(BM)with specialized columnar epithelium(SCE)is high risk of Barrett’s adenocarcinoma, however, what finding in endoscopy could reflect SCE is unclear. Methods:We investigated subjects who underwent upper gastrointestinal endoscopy(UGI)since February 2008 until August 2012. In subjects with endoscopically suspected esophageal metaplasia(ESEM), we investigated the pathological findings of biopsy obtained from ESEM. ESEM was categorized as(1)ultrashort(USBE)<1cm,(2)1cm<=short(SSBE)<3cm, and(3)long(LSBE)>=3cm. ESEM was categorized as palisade vessel(type-P)and non-palisade vessel(type-N)endoscopically, and as SCE type and non-SCE type pathologically. We investigated the correlation between these endoscopic findings and SCE. Result:1012 cases underwent UGI and the subjects with ESEM were 269 cases. Among 269 subjects with ESEM, 107 cases were obtained esophageal biopies from ESEM(M/F 68/39, mean age 60.7±12.2). USBE, SSBE and LSBE were found in 67, 40 and 0 cases. Type-P and N were found in 81 and 26 cases. SCE and non-SCE were found in 24 and 83 cases. Detection rate of SCE of type-N(46.1%)was higher than that of type-P(14.8%)(p<0.01). There was no different detection rate in SCE between USBE and SSBE. Conclusion:Presence of SCE in Type-N ESEM was more frequent than Type-P. The length of BM was not relevant to SCE. These results suggested that type-N ESEM regardless the length of BM should be important to consider SCE.
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