| 共同演者 |
Ishigaki Saori（Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Japan）, Suzuki Mio（Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Japan）, Takahashi Masakazu（Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Japan）, Ono Shoko（Division of Endoscopy, Hokkaido University Hospital, Japan）, Nakagawa Manabu（Division of Endoscopy, Hokkaido University Hospital, Japan）, Yamamoto Junji（Division of Endoscopy, Hokkaido University Hospital, Japan）, Nakagawa Soichi（Division of Endoscopy, Hokkaido University Hospital, Japan）, Mabe Katsuhiro（Division of Endoscopy, Hokkaido University Hospital, Japan）, Shimizu Yuichi（Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Japan）, Kato Mototsugu（Division of Endoscopy, Hokkaido University Hospital, Japan）, Sakamoto Naoya（Department of Gastroenterology, Hokkaido University Graduate School of Medicine, Japan）, Asaka Masahiro（Depertment of Cancer Preventive Medicine, Hokkaido University Graduate School of Medicine, Japan） |
| 抄録 |
【Aim】It had been revealed that H.pylori eradication reduced the risk for gastric cancer. However, gastric cancer is sometimes discovered after successful eradication of H.pylori. The aim of this study is to clarify the clinicopathlogical features of gastric cancers, which detected after successful eradication.【Method】We performed the multi-center, retrospective survey about the gastric cancer cases detected after H.pylori eradication in Japan.【Results】A total 424 gastric cancer cases from 34 institutions were included this study.17 cases detected before 1 year after eradication, while 28 cases detected 10 years or more after eradication. We compared between the cases detected before 5 years（A）and the cases over 5 years（B）. Advanced cancers and large lesions（＜1cm）were significantly more detected in the group B. When eradication had been done for peptic ulcer, the half of cancer cases detected over 5 years, while for gastric adenoma, MALT lymphoma and gastric cancers, most cases detected before 5 years. Depressed type, diffuse type and large lesions（＜1cm）were more detected in the primary cancers than in metachronous cancers.【Conclusion】Gastric cancer was detected even after 10 years or more, and the clinicopathlogical features, such as lesion or histology, were different by baseline diseases or degree of gastric mucosal atrophy. Our study revealed that follow-up endoscopic examination is necessary even after successful H. pylori eradication for a long time. |
