セッション情報 International Session3(消化器内視鏡学会・消化器病学会合同)

IgG4-related disease and endoscopy

タイトル 消IS3-2:

Importance of endoscopic retrograde pancreatography in diagnosis of segmental/focal type 1 autoimmune pancreatitis.

演者 K. Sumimoto(The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University)
共同演者 K. Uchida(The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University), K. Okazaki(The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University)
抄録 Background: In 2011, the International Association of Pancreatology proposed the International Consensus Diagnostic Criteria (ICDC). The differential diagnosis of segmental/focal type autoimmune pancreatitis (AIP) and pancreatic cancer using imaging findings is sometimes difficult. We studied diagnostic sensitivity between computed tomography (CT) and endoscopic retrograde pancreatography (ERP), and proposed a diagnostic algorithm for AIP.
Methods: Thirty AIP patients and 30 pancreatic cancer patients were retrospectively studied. Pancreas imaging on CT and ERP were independently evaluated by 3 pancreatologists (5, 10, and 20 years of career experience). We compared diagnostic sensitivity between CT and ERP. Diagnostic sensitivities of endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA), cytology of pancreatic juice, brushing cytology of pancreatic duct, bile cytology and bile duct biopsy were also compared.
Results: Diagnostic sensitivities of combination with CT and ERP in segmental/focal type AIP were significantly higher than single imaging (26% in CT (P < 0.01) or 35% in ERP (P < 0.05) vs 63% in CT+ERP), but not significantly different in the diffuse type. Diagnostic sensitivities of EUS-FNA, cytology of pancreatic juice, brushing cytology of pancreatic duct, bile cytology and bile duct biopsy were 100% (5/5), 56% (5/9), 100% (5/5), 73% (11/15), and 50% (8/16).
Conclusions: The combination of ERP and CT is important to carry out differential diagnosis of pancreatic cancer and segmental/focal type AIP.
索引用語 Autoimmune pancreatitis, Endoscopic retrograde pancreatography