| 抄録 |
BACKGROUNDS: Pancreatic manifestation of IgG4-related disease is also known as type 1 AIP according to the international consensus diagnostic criteria (ICDC) for AIP. The aim of this study is to clarify the role of EUS in differential diagnosis of type 1 and type 2 AIP. METHODS: Thirty-six patients with AIP based on the ICDC who underwent EUS prior to treatment were enrolled in this study. EUS findings were retrospectively evaluated according to the specific features of AIP described previously (Hoki, J Gastroenterol, 2009) and EUS features of early stage chronic pancreatitis (ECP)(Miyagawa, Suizo, 2009). RESULTS: Of 36 patients, 31 were diagnosed as type 1 AIP (definitive, 29; probable, 2) and the rest of 5 were diagnosed as type 2 AIP (definitive, 4; probable, 1). On the basis of AIP findings, diffuse hypoechoic (DH)(26/31 in type 1 and 2/5 in type 2, respectively; P=0.029) and lymphadenopathy (LN)(22/31 and 1/5, respectively; P=0.028) were higher in type 1 AIP. On the basis of ECP findings, dilatation side branches (0/31 and 1/5, respectively; P=0.012) was higher in type 2 AIP. CONCLUSION: DH and LN of specific features of AIP are useful to distinguish type 1 from type 2 AIP. On the other hand, EUS features of ECP are not useful for differential diagnosis of type 1 and 2 AIP. |
