セッション情報 International Session3(消化器内視鏡学会・消化器病学会合同)

IgG4-related disease and endoscopy

タイトル 消IS3-8:

The role of EUS in diagnosis and treatment of autoimmune pancreatitis.

演者 S. Omoto(Department of Gastroenterology and Hepatology of Kinki University)
共同演者 M. Kitano(Department of Gastroenterology and Hepatology of Kinki University), M. Kudo(Department of Gastroenterology and Hepatology of Kinki University)
抄録 BACKGROUND AND OBJECTIVE:Although EUS is useful for diagnosis of tumors in the pancreas,the EUS findings are not employed in the International criteria for autoimmune pancreatitis(AIP){ICDC2008} and Clinical diagnostic criteria for AIP 2011{CDC2011}. OBJECTIVE:The aim of the study was to investigate the role of EUS in diagnosis and treatment of AIP.
METHODS:EUS findings of 21 patients that were diagnosed with AIP using the ICDC2008 and CDC2011 were re-evaluated. EUS findings included the following features ; a:lobularity, b:strands, c:hyperechoic foci, d:duct penetrating sign, e:cupsule like rim, f:mass forming pancreatitis, g:isoenhancement on contrast enhanced EUS. Changes in EUS findings were evaluated 2 months after the steroid therapy.EUS-FNA was performed in all patients.
RESULTS
EUS findings:a,b,c,d,e,f and g were observed in 81%,100%,100%,86%,48%,80% and 81%,respectively. Other imaging modalities failed to exclude a pancreatic carcinoma in 11 patients with focal type of AIP. However,EUS images and histology obtained by EUS-FNA showed typical findings of AIP in these patients.In 9 patients who received steroid therapy,lobularity and strands disappeared.
CONCLUSION: EUS is useful for discrimination of focal AIP from pancreatic carcinoma and evaluation of response to steroid therapy.
Strands,lobularity observed by EUS may reflect the disease activity.
索引用語 AIP, pancreas