| セッション情報 |
International Session3(消化器内視鏡学会・消化器病学会合同)
IgG4-related disease and endoscopy
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| タイトル |
内IS3-10：The diagnosis of autoimmune pancreatitis by EUS-FNA based on the International Consensus Diagnostic Criteria (ICDC).
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| 演者 |
A. Kanno（Division of Gastroenterology, Tohoku University Graduate School of Medicine） |
| 共同演者 |
A. Masamune（Division of Gastroenterology, Tohoku University Graduate School of Medicine）, T. Shimosegawa（Division of Gastroenterology, Tohoku University Graduate School of Medicine） |
| 抄録 |
Background: It is controversial whether EUS-FNA is useful for the diagnosis of autoimmune pancreatitis (AIP). Objective: To evaluate the usefulness of EUS-FNA in the histopathological diagnosis of AIP.Design: A single-center retrospective study.Patients: Histopathological examination was performed on pancreatic specimens obtained from 378 patients including 34 with AIP by EUS-FNA. Results: EUS-FNA using a 22- or 19-G needle provided adequate tissue samples for histopathological evaluation; more than 10 high power fields (HPFs) were available for evaluation in 29 of 34 (85 %) patients. The mean CD38-positive plasma cell count was 65.1/HPF. The mean IgG4-positive plasma cell count was 22.2 /HPF. Obliterative phlebitis was observed in 17 of the 34 (50 %) patients. In the context of the International Consensus Diagnostic Criteria for AIP, 22 of 34 patients were level 1 (positive for 3 or 4 items), and 6 patients were level 2 (positive for 2 items). Collectively, 28 of 34 patients had lymphoplasmacytic sclerosing pancreatitis based on the ICDC. One patient was diagnosed with type 2 AIP since a granulocyte epithelial lesion was identified. Conclusions: EUS-FNA provides tissue samples that are adequate for histopathological evaluation, contributing to the histological diagnosis of AIP. |
| 索引用語 |
AIP, ICDC |
