セッション情報 International Session4(消化器内視鏡学会・消化器病学会合同)

Achieving high quality colorectal ESD

タイトル 内IS4-7:

Endoscopic Submucosal Dissection for Colonic Tumors -Risk factors for Procedure-related Intestinal Perforation-

演者 Y. Kojima(Department of Gastroenterology, Yamanashi Central Hospital)
共同演者 Y. Suzuki(Department of Gastroenterology, Yamanashi Central Hospital), M. Omata(Department of Gastroenterology, Yamanashi Central Hospital)
抄録 Background: Endoscopic Submucosal Dissection (ESD) is quite unique in the ideas to completely remove gastric tumors en bloc by dissecting into submucosal layer, but requires certain expertise. This is more so for the neoplasm in the colon which has thinner wall. In this study, we conducted statistical analysis of factors which are related to the procedure-related intestinal perforation on colonic ESD cases. Aims: To elucidate the factors which are related to the procedure-related colonic perforation. Subjects: 233 cases (male 138/female 95, median age 69 years, range 33-87 years) underwent ESD between January 2007 and December 2012. Results: Perforation occurred in 16 cases (7.2 %). There was no significant difference in size of the lesions which were divided based on median size of the lesions, 22 mm. There was no significant difference in perforation rate in each year. There was no significant difference in perforation rate between doctors, locations of the lesions, previous biopsy cases and between schistosomal and non-schistosomal cases. There was a significant difference in perforation rate in histology (p<0.001). Carcinoma with submucosal invasion more than 1000 μm had higher perforation rate (5/14, 35 %) significantly (p<0.001).Conclusions: Histology of the lesions was a significant factor which related to perforation. To avoid procedure-related perforations, preoperative diagnosis of the depth of the lesion is an important factor.
索引用語 ESD, Colonic tumors