セッション情報 International Session6(消化器内視鏡学会・消化器病学会合同)

Strategy of biliary drainage for hilar biliary strictures

タイトル 内IS6-7追:

Endoscopic Bilateral Stent-in-stent Placement with Modified Large Cell Niti-S Stents for Malignant Hilar Biliary Obstruction

演者 H. Kogure(Department of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of TokyoDELIMITERDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo)
共同演者 H. Isayama(Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo), K. Koike(Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo)
抄録 Background: Endoscopic bilateral self-expandable metallic stent (SEMS) placement in a stent-in-stent method for malignant hilar biliary obstruction is technically challenging. Technical difficulties in the initial placement and reinterventions for stent occlusion are disadvantages inherent to this stent-in-stent method. We previously reported the feasibility of Niti-S large cell D-type biliary stents (LCD). This study evaluated the efficacy of bilateral SEMS placement using modified LCD with large and uniform cells, a slimmer delivery system and high radial force.Methods: Forty consecutive patients with unresectable malignant hilar biliary obstruction underwent endoscopic bilateral placement of modified LCD in a stent-in-stent method.Results: Single-session and final technical success rate was 95% and 100%, respectively. Functional success rate was 93%. Stent occlusion occurred in 14 patients (35%) because of sludge (n = 8), tumor ingrowth (n = 5), or tumor bleeding (n = 1). Endoscopic bilateral reintervention was technically easy and successful: 7 patients had stent clearance by balloon sweeping and 7 had plastic stent placement. According to the Kaplan-Meier analysis, median survival and stent patency were 220 days and 169 days, respectively.Conclusions: Modified LCD achieved a high technical success rate both in the initial stent-in-stent placement and in bilateral reinterventions in patients with malignant hilar biliary obstruction.
索引用語 bilateral biliary drainage, self-expandable metallic stent