セッション情報 ポスターセッション(肝臓学会)

NAFLD・NASH7

タイトル 肝P-327:

Predisposing factors of delirium for non alcoholic liver cirrhosis with living donor liver transplantation

演者 S.-H. Wang(Transplantation Center of Changhua Christian Hospital)
共同演者 C.-E. Hsieh(Transplantation Center of Changhua Christian Hospital), J.-Y. Wang(Department of Health Care Administration, Asia University), Y.-L. Chen(Transplantation Center of Changhua Christian Hospital)
抄録 Delirium occurs in most living donor liver transplant (LDLT) patients and is independently associated with longer ICU and hospital days.Objective:Predisposing delirium factors of non alcoholic liver cirrhosis with living donor liver transplantation in intensive care units.Method:A prospective cohort investigation of 54 non alcoholic liver cirrhosis LDLT patients at a medical center between January 2010 to December 2012.Preoperative factors include HCC, MELD score and hepatic encephalopathy. Postoperative factors include operative time, blood loss, APACHE II score, endotracheal tube days and infection. ICU and hospital days were used as outcome variables to evaluate the impact of delirium. ICU nursing staff assessed delirium and level of consciousness at least twice per day by using CAM-ICU. Stepwise regression method was used to independent relationship between delirium and clinical parameters of patients.Result:31.5%(17/54) LDLT patients experienced at least one episode of delirium. Delirium occurred average on the 8.4 day and maintain 6.0 days.APACHE II score(OR=1.25, 95%CI=1.09, 1.43) was the important risk factor of delirium. Besides,delirium group ICU stay 21.5 days and hospital days 51.4 days were significantly higher than the no delirium group.Conclusion:Within 24 hours after LDLT is a golden time and APACHE II score is the pivotal factor of delirium.High-quality critical care, stabilize vital signs can reduce the incidence of delirium.
索引用語 living donor liver transplantation, delirium