セッション情報 The 4th International Forum

Short Oral Presentations(Pancreaticobiliary disorders 1)

タイトル IF-SOP-12:

The role of gastrodeuodenal stent intervention in the treatment of pancreatic cancers

演者 Sato Takamitsu(Department of Gastroenterology, Aichi Cancer Center Hospital, JapanDELIMITERDivision of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan)
共同演者 Hara Kazuo(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan), Mizuno Nobumasa(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan), Hijioka Susumu(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan), Imaoka Hiroshi(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan), Maeda Shin(Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan), Nakajima Atsushi(Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan), Kubota Kensuke(Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan), Yamao Kenji(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan)
抄録 Background and study aims:Some pancreatic cancers are complicated with malignant gastric outlet obstructions(GOOs), and which often disturb the treatment course. Self-expandable metallic stents(SEMSs)have mainly been used for the palliation of GOO. We examined the clinical role of SEMS interventions for the patient with pancreatic cancer.
Patients and methods:This multicenter study included 54 patients with GOO caused by pancreatic cancer(mean age 64.3±10.2 years;26 men)and 70 SEMS interventions(54 first and 16 additional interventions)at Aichi Cancer Center Hospital and Yokohama City University Hospital. We estimated the success rate, efficacy, complication, stent dysfunction, stent patency, eating period, post-procedure therapy and biliary drainage.
Results:The technical and clinical success rates were 100% and 82.9% respectively;the median recovered GOO scoring system after intervention was 2. The early and late complication rates were 22.9% and 8.6%. The stent dysfunctions occurred in 31.4% of cases. The median stent patency was 172 days and 68.5% of the patients maintained oral intake at the time of study termination or death. After intervention, 59.3% of the patients could take chemotherapy and 2 patients could be resected surgically together with SEMS, after chemotherapy. Forty eight patients required biliary drainage;29 endoscopic biliary drainages(via the papilla);12 endoscopic ultrasonography-guided biliary drainages;7 percutaneous transhepatic biliary drainages.
Conclusions:SEMS intervention could enable patients with GOO to take continual therapies, therefore it would be necessary and helpful in the better treatment of pancreatic cancers.

Key words:pancreatic cancer, gastric outlet obstruction, gastrodeuodenal stent
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