| セッション情報 | The 4th International ForumShort Oral Presentations（Pancreaticobiliary disorders 1） |
|---|---|
| タイトル | IF-SOP-13：Predictors of failed stenting during Endoscopic Retrograde Cholangiopancreatography（ERCP）in malignant biliary obstruction |
| 演者 | Chu Michael V.（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines） |
| 共同演者 | Pascua Eileen O.（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Malbog Milben（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Palaganas Noel（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Lester Sy Mark（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Coronel Gerby（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, De Lusong Mark Anthony（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Domingo, Jr Felix（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines）, Naval Marichona（East Avenue Medical Center, Section of Gastroenteorlogy, Philippines） |
| 抄録 | INTRODUCTION Malignant biliary obstruction secondary to Pancreatic head malignancy and Cholangiocarcinoma often results in obstructive jaundice. The primary role of ERCP is to provide relief of obstruction through stent insertion. Technical difficulty of ERCP stent insertion usually results in percutaneous biliary drainage. This study aims to determine the risk factors for failed ERCP stent insertion in Malignant Obstruction. METHODS This is a retrospective, two-center study involving patients with Pancreatic Cancer and Cholangiocarcinoma who underwent ERCP from January 2010 to June 2013. Multivariate logistic regression was done to determine factors associated with failure of stenting. Significant variables were used to construct a predictive model in determining success or failure of stent insertion. RESULTS A total of 81 patients underwent ERCP due to malignant obstruction and 18（22%）of these had failed stent insertion. Among patients with Cholangiocarcinoma, 28%（6/21）had failed ERCP stenting, while 20%（12/60）of patients with Pancreatic Cancer resulted in percutaneous drainage. Factors associated with failure includes（OR；95% CI）：Common Bile Duct diameter（3.12；1.76-5.512）, size of mass（1.62；1.024-2.231）, total bilirubin（0.946；0.631-1.261）and duration of jaundice（1.04；1.01-1.077）. CONCLUSION This study concludes that these factors are key predictors of stenting failure during ERCP. This suggests the use of percutaneous biliary drainage as first line modality if these factors are prominent. The predictive model constructed may help predict success and failure of stenting, although validation in other centers is suggested. KEY WORDS：cholangiocarcinoma, pancreatic cancer, stenting, ERCP |
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