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Is the WHO 2010 classification sufficient to clearly characterize pancreatic neuroendocrine carcinoma?
Hijioka Susumu(Department of Gastroenterology, Aichi Cancer Center Hospital, Japan)
Background:The WHO 2000 classification of pancreatic neuroendocrine tumors(pNET)addressed morphological differentiation as the first criterion;however, the 2010 classification is based on histo...

第100回日本消化器病学会総会 > Short Oral Presentations(Pancreaticobiliary disorders 2)

Pancreatic Ductal Adenocarcinoma(PDAC):Identification of compounds that inhibit NUPR1 protein function in cell culture
Abian Olga(Aragon Health Science Institute, Spain)
Because pancreatic cancer is often diagnosed at a late stage, surgical removal of the tumor is often difficult, if not impossible. Pancreatic ductal adenocarcinoma, or PDAC, is by far the most common ...

第100回日本消化器病学会総会 > Short Oral Presentations(Pancreaticobiliary disorders 2)

Loss of runt-related transcription factor 3 induces gemcitabine resistance via increasing the expression of multidrug resistant protein in pancreatic cancer
Horiguchi Shigeru(Department of Gastroenterology & Hepatology, Okayama University Graduate School of Medicine, Japan)
Background and Aim:Runt-related transcription factor 3(RUNX3)is a tumor suppressor gene discovered in gastric cancer. RUNX3 is lost or decreased in various cancer tissues, including pancreatic ...

第100回日本消化器病学会総会 > Short Oral Presentations(Pancreaticobiliary disorders 2)

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts
Kanda Mitsuro(Department of Gastroenterological Surgery(Surgery II), Nagoya University Graduate School of Medicine, Japan)
Objective;Pancreatic cysts are commonly detected in patients undergoing pancreatic imaging. Better approaches are needed to characterise these lesions. In this study we evaluated the utility of...

第100回日本消化器病学会総会 > Short Oral Presentations(Pancreaticobiliary disorders 2)

Investigation of biological characteristics of biliary tract cancers to establish a novel molecular-targeted therapy
Yokoyama Masaaki(Kyorin University, Japan)
<Purpose>
The purpose of this study is to investigate various genes mutations and protein overexpression in biliary tract cancer(BTC), in order to establish most optimal molecular targeted therapy....

第100回日本消化器病学会総会 > Short Oral Presentations(Pancreaticobiliary disorders 2)