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検索結果は5件です。
- Apoptosis Promotes Oncogenic Potential in DEN-administrated Mice
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Tanaka Satoshi(Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan)
Background and Aim:Apoptosis serves as an important mechanism by removing DNA damaged-cells and is considered to inhibit carcinogenesis. On the other hand, hepatocyte apoptosis is a key feature...
第99回日本消化器病学会総会 >
Oxidative Stress and Apptosis
- Antioxidant Has a Therapeutic Potential for HCC Driven by Chronic Liver Injury
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Hikita Hayato(Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Japan)
Background and Aim:Continuous hepatocyte apoptosis is a hallmark for chronic viral hepatitis or non-alcoholic steatohepatitis, which is a high-risk condition for HCC. Although we have reported ...
第99回日本消化器病学会総会 >
Oxidative Stress and Apptosis
- Changes of Cytokines in Cirrhosis Patients with Advanced Hepatocellular Carcinoma Treated by Sorafenib
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Nagai Hidenari(Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, Toho University School of Medicine, Japan)
BACKGROUND:Tumor necrosis factor(TNF)is known to induce apoptosis of tumor cells by binding to TNF-related apoptosis-inducing ligand. Binding of the Fas ligand on cytotoxic T lymphocytes to the Fas re...
第99回日本消化器病学会総会 >
Oxidative Stress and Apptosis
- Suppressed Mitophagy in Transgenic Mice Expressing Hepatitis C Virus Polyprotein
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Hara Yuichi(Hepatology and Pancreatology, Kawasaki Medical School, Japan)
We previously demonstrated that the presence of impaired mitochondria is critical for HCV-associated hepatocarcinogenesis in mice. Impaired mitochondria are selectively eliminated through autophagy-de...
第99回日本消化器病学会総会 >
Oxidative Stress and Apptosis
- Low-dose Interferon Improved Alpha-fetoprotein Levels and Iron Metabolic Disorder in Patients with Hepatitis C Virus Infection Bearing Non-interferon Sensitive IL28B Single Nucleotide Polymorphisms
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Takeda Tsutomu(The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine(NCGM), Japan)
Background and Aim:Long-term, low-dose Peg-IFN administration has been shown to reduce the incidence of hepatocellular carcinoma in patients with liver cirrhosis infected with HCV. The aim of the stud...
第99回日本消化器病学会総会 >
Oxidative Stress and Apptosis
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