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検索結果は5件です。
- RNA-binding protein HuR and microRNAs in gut epithelial homeostasis and diseases
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Wang Jian-Ying(Cell Biology Group, Departments of Surgery and Pathology, University of Maryland and BVAMC, USA)
The intestinal epithelium is a rapidly self-renewing tissue in the body and its homeostasis is preserved through strict regulation of cell proliferation, apoptosis, and differentiation. Emerging data...
第100回日本消化器病学会総会 >
I Drug-associated GI Injury:Advances of the pathogenesis and recent clinical topics 1. Advances of the pathogenesis(a)Mucosal injury and prostaglandins
- Bile acid activated receptors regulates integrity of gastrointestinal mucosa
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Fiorucci Stefano(Department of Surgery and Biomedical Sciences, University of Perugia, Italy)
Bile acid-activated receptors are a family of membrane and nuclear receptors activated by bile acids. This family included the G-protein coupled receptor GP-BAR1 and at least four nuclear receptors(FX...
第100回日本消化器病学会総会 >
I Drug-associated GI Injury:Advances of the pathogenesis and recent clinical topics 1. Advances of the pathogenesis(a)Mucosal injury and prostaglandins
- Roles of prostanoids in the maintenance of gastric mucosal integrity and the healing of gastric ulcers
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Majima Masataka(Department of Pharmacology, Kitasato University School of Medicine, Japan)
Prostanoids play important roles in modulation of gastric mucosal integrity. Prostacycline(PGI2)exhibits protective actions against ethanol-induced gastric mucosal damages via the interacti...
第100回日本消化器病学会総会 >
I Drug-associated GI Injury:Advances of the pathogenesis and recent clinical topics 1. Advances of the pathogenesis(a)Mucosal injury and prostaglandins
- Identification of a unique NSAID, fluoro-loxoprofen with gastroprotective activity
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Mizushima Tohru(Faculty of Pharmacy, Keio University, Japan)
We previously proposed that direct cytotoxicity of NSAIDs due to their membrane permeabilization activity, together with their ability to decrease gastric prostaglandin E2, contributes to p...
第100回日本消化器病学会総会 >
I Drug-associated GI Injury:Advances of the pathogenesis and recent clinical topics 1. Advances of the pathogenesis(a)Mucosal injury and prostaglandins
- Rescuing from NSAID-induced GI injury;PUFAs, SAC, and more
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Hahm Ki. Baik(CHA University School of Medicine and Cancer Prevention Research Center, Korea)
Nonsteroidal anti-inflammatory drugs(NSAIDs)represent a critically important class of medications useful in clinic. The focus of NSAID use has recently centered on gastrointestinal(GI)side effects as ...
第100回日本消化器病学会総会 >
I Drug-associated GI Injury:Advances of the pathogenesis and recent clinical topics 1. Advances of the pathogenesis(a)Mucosal injury and prostaglandins
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