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Macrophage Therapy for Liver Fibrosis and Regeneration
S. J. Forbes(The University of Edinburgh)
Macrophage therapy for liver fibrosis and regenerationSJ ForbesDuring chronic liver injury there is deposition of excess collagen scar, and impaired liver regeneration from hepatic progenitor cells (H...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

The development of a less-invasive liver regeneration therapy using cultured bone marrow derived cells for cirrhotic patients
T. Takami(Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine)
We have developed autologous bone marrow cell infusion (ABMi) therapy, which was a method of liver regeneration for cirrhotic patients using non-cultured autologous whole bone marrow (BM) cells...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

Cell-based immunotherapy for HCC: our experiences and future directions
N. Iida(Department of Gastroenterology, Graduate School of Medicine, Kanazawa University)
Treatments targeting hepatocellular carcinoma (HCC) in advanced stage are often discontinued due to systemic adverse effect. Immunotherapy is a promising treatment which specifically targets HCC. A su...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

Novel immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation.
M. Ohira(The Second Department of Surgery, Hiroshima University)
Tumor recurrence is the main limitation of liver transplantation (LT) in patients with hepatocellular carcinoma (HCC) and can be promoted by immunosuppressants. However, there is no prevention or trea...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

A next generation sequencing (NGS)-based approach toward developing new adeno-associated virus (AAV) vectors for gene therapy
H. Nakai(Department of Molecular & Medical Genetics, Oregon Health & Science University)
AAV vectors are among the most attractive gene delivery vehicles for human gene therapy. Promising therapeutic efficacy of AAV gene therapy has been reported in several clinical trials, including live...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

AAV (adono-associated virus) vector-mediated gene therapy for Parkinson's disease and hemophilia
K. Ozawa(Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical University)
AAV (adeno-associated virus) vectors are considered to be promising gene-delivery vehicles for gene therapy, because they are derived from non-pathogenic virus, efficiently transduce non-dividing cell...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

"Human artificial chromosomes for gene- and cell-therapies"
M. Oshimura(Graduate School of Medical Science,Tottori University)
Random integration of conventional gene delivery vectors such as viruses, plasmids, P1 phage-derived artificial chromosomes, bacterial artificial chromosomes and yeast artificial chromosomes can be as...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

Image-guided, Hydrodynamic Gene and Cell Delivery through the Liver: Toward Clinical Applications
K. Kamimura(Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University)
The efficient and safe in vivo gene delivery to the hepatocytes is one of great milestones for gene and cell therapy treating various genetic and acquired disorders. For this purpose, we have f...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

The Way to Clinical Applications of human Pluripotent Stem Cells
T. Aoi(Division of iPS cell Applications, Department of Internal Medicine, Kobe University)
Human embryonic stem (ES) cells have been expected as resources for regenerative medicine because of their pluripotency and ability to self-renew. In 2007, human induced pluripotent stem (iPS) cells w...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects

D. Liu(Department of Pharmaceutical and Biomedical Sciences, University of Georgia)
...

第55回日本消化器病学会大会Gene therapy and cell therapy through the liver; current aspects and future prospects